Got Books Here: A Poem

What got us here will not get us there.

This is an exciting yet trying time for people living with neuromuscular diseases and those who care for them. The exciting aspect is that at last the advances in genetics and translational research have resulted in clinical trials testing novel compounds. Examples include the exon-skipping approaches in Duchenne Muscular Dystrophy (DMD). Resulting from a sophisticated understanding of the cons...

How we got from there to here and back.

Edward H. Angle dominated orthodontic armamentarium, diagnosis and treatment planning for almost a half century until Charles Tweed successfully challenged his mentor's nonextraction mantra. The ensuing diagnostic regimen used by Tweed, however, proved to have serious limitations and clearly resulted in the extraction of too many teeth. This caused a subsequent deterioration of soft tissue appe...

ICU Rounds: "What We've Got Here Is Failure to Communicate".

ZHOUPI, a unique and highly conserved bHLH transcription factor, controls both endosperm breakdown and embryonic surface formation during Arabidopsis seed development. We have demonstrated that these two processes are distinct, and that ZHOUPI regulates embryonic surface formation via a signaling pathway mediated by the subtilisin-like serine protease ABNORMAL LEAF SHAPE1, and the receptor-kina...

Life: A Poem

A critical care holiday poem.